Thoughts and Ramblings of Life in US and the Philippines(Marinduque) and other miscellaneous topics close to my Heart.
Welcome to Marinduque-My Island Paradise
If this is your first time in my site, welcome! If you have been a follower, my heartfelt thanks to you, also. Help me achieve my dream, that someday, Marinduque will become a world tourist destination not only on Easter Week, but also whole year round. You can do this by telling your friends and relatives about this site. The photo above is Mt Malindig in Torrijos. Some of the photos and videos on this site, I do not own. However, I have no intention on the infringement of your copyrights. Cheers!
Sunday, March 29, 2020
The Recent Wedding Photos of Arvy and Rosiel at CDM
Arvy Anep Aibur and Rosiel Piedragoza Wedding at CDM-March 7, 2020
For a short video visit the following Facebook page:
https://www.facebook.com/razastillsandmotions/videos/654125195156022/
Saturday, March 28, 2020
Paintings of the Chateau Du Mer Beach House
The
above paintings of the Chateau Du Mer Beach House in Amoingon, Boac
Marinduque, Philippines are a courtesy of the Late Rene Nieva-Macrine's
first cousin. The technique varies from Impressionism, Dadaism,
Expressionism, Cubism,watercolor, sponge dabbed, etc..
Do you have a Favorite? For more information visit the link below:
https://www.tripadvisor.com/LocationPhotoDirectLink-g1026955-d1159553-i33236474-Chateau_Du_Mer_Beach_Resort-Marinduque_Island_Mimaropa.html
Do you have a Favorite? For more information visit the link below:
https://www.tripadvisor.com/LocationPhotoDirectLink-g1026955-d1159553-i33236474-Chateau_Du_Mer_Beach_Resort-Marinduque_Island_Mimaropa.html
Wednesday, March 25, 2020
The Rare Flora and Fauna of the Philippines
This is one of the best documentary on the beauty, flora and fauna of the Philippines that I have viewed.-Untamed Philippines
Two Episodes of this documentary are now available at the National Geographic Channel. Enjoy!
https://www.nationalgeographic.com.au/tv/untamed-philippines/
https://youtu.be/4rxc_qiEWvI
Meanwhile, enjoy this video Of Yong Nieva visiting and singing to Macrine, 4 years ago at Chateau Du Mer, Marinduque
https://www.facebook.com/david.b.katague/videos/10206320460666763/
Two Episodes of this documentary are now available at the National Geographic Channel. Enjoy!
https://www.nationalgeographic.com.au/tv/untamed-philippines/
https://youtu.be/4rxc_qiEWvI
Meanwhile, enjoy this video Of Yong Nieva visiting and singing to Macrine, 4 years ago at Chateau Du Mer, Marinduque
https://www.facebook.com/david.b.katague/videos/10206320460666763/
Saturday, March 21, 2020
Trump's Wonder Cure Drugs for Covid-19
I received the following letter today from a PAASE member, detailing the dangers of Chloroquine and hydroxychloroquine approved by FDA for malaria but not for corona virus as Trump falsely proclaimed in TV the other day. Dr Fauci clarified that Trump announcement was not true. Here's the letter for your information.
"Trump is wrong! It is not meant for prophylaxis or prevention. It should be reserved for high-risk COVID + cases admitted in hospital, and is part of many protocols (together with Azithromycin).
People circulating this, including their recommended prophylactic
dose for adults and children, are dangerous and must be stopped:
The Vibermongerers and Viberquackdocs are even posting the dose:
“Start Chloroquine 500 mg one tablet per week as a prophylaxis for covid
for adults. For kids take in syrup form and equivalent to 8.3 mg per
week dose. Prophylaxis can be continued for 6 to 8 weeks.” NO baseline
screening (retina, heart, liver, G6PD)! Dangerous!
Chloroquine and hydroxychloroquine belong to the quinolone family.
Although their therapeutic and toxic doses differ, they are related
drugs with similar clinical indications for use and similar
manifestations of retinal toxicity.
Shown to cause severe hypoglycemia including loss of consciousness
that could be life-threatening in patients treated with or without
antidiabetic medications; patients should be warned about risk of
hypoglycemia and associated clinical signs and symptoms; patients
presenting with clinical symptoms suggestive of hypoglycemia during
treatment with chloroquine should have blood glucose level checked and
treatment reviewed as necessary.
Cases of cardiomyopathy resulting in cardiac failure, in some cases
with fatal outcome, QT interval prolongation, torsades de pointes, and
ventricular arrhythmias reported; Caution with hepatic disease,
alcoholism, and coadministration with other hepatotoxic drugs; Caution
with history of auditory damage; May provoke seizures in patients with
history of epilepsy.
May cause hemolysis in glucose-6 phosphate dehydrogenase (G-6-PD)
deficiency; blood monitoring may be needed as hemolytic anemia may
occur, in particular in association with other drugs that cause
hemolysis.
- Chloroquine
- Antimalarial w/ antiviral activity
- interferes w/ viral entry by changing acidification inside of cell
- inhibits SARS-CoV2 co-receptor
- immune modulating activity (we don’t know yet if that’s good or bad for COVID-19)
- Inexpensive, long track record
- In vitro has similar effectiveness against SARS-CoV2 as Remdesivir
- Reported to improve pneumonia, viral clearance, and disease course from China cases (but we don’t have RCT trial data or robust cases of this)
- Requires higher dose than for malaria: 500mg BID
- Limited supply in the US
- Hydroxychloroquine: related to chloroquine
- Preferred as alternative: can increase PO dose, has decreased drug interactions, and is more widely tolerated
- May be more potent against SARS-CoV2 than chloroquine (in vitro studies)
Personal Note: As a retired FDA Chemistry Team Leader in the Division Of Anti-Infective Drug Products, I am familiar of the side effects and dangers of Chloroquine if a proper dosage is not given to the patients. What works in the Lab(in vitro studies) do not necessary translate as safe and effective to humans!
Thursday, March 19, 2020
First Day of Spring in Northern California
| Greetings from my real estate broker! | |
Hi David,
With the damp and cold ushered out for the year, enjoy the lively colors, flowery fragrances, and gentle warmth of the Spring season.
Best wishes for a wonderful season!
|
Tuesday, March 17, 2020
New and Old Photos from My Album
New and Old Photos from My Album
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| Ditas and Carenna, 2020 It is time to forget the corona virus pandemic and stock market collapse for a few minutes and enjoy the following old and new photos from my Album! |
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| Ditas and Governor Gauvin Newsom, 2020 |
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| Yosemite National Park, Winter, 2020 |
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| Homemade Chili Relleno with Cholula Hot Sauce |
| A Carenna and Ditas Blanket |
| Macrine Eating Breakfast with Caretaker's Assistance, 2020 |
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| Macrine's High School Graduation-She is Seating First on the Right-Front Row Meanwhile, enjoy this short video of the wedding of Amiel and Erika, May, 1019 with CDM as the venue |
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