While there isn't a single "gay gene," research indicates that homosexuality has a genetic component, with genes on chromosomes 8 and Xq28identified as influencing same-sex sexual orientation. This means that genetics play a role in the development of sexual orientation, but it's not the sole determinant, and other factors like prenatal hormone exposure and environmental influences are also involved.
Sexual orientation appears to be influenced by a complex mix of genetics, biology, and environment. Large genetic studies — like the 2019 Science paper that analyzed the DNA of nearly half a million people — have found that:
Multiple genetic variants are linked to same-sex sexual behavior, but each has only a very small effect.
These variants are not deterministic — having them doesn’t mean a person will be gay, and not having them doesn’t mean they won’t be.
The combined genetic influence explains less than one-third of the variation in sexual behavior, meaning non-genetic factors play a large role too.
Other biological factors — like hormonal exposure in the womb or epigenetic changes — may interact with genetics to influence sexual orientation.
So, the most accurate answer is: It’s polygenic (involving many genes) and shaped by other biological and environmental influences — there’s no single “gay gene.”
1. What major studies actually found about genetics & homosexuality
The biggest and most cited modern study is:
Ganna et al., 2019 — Science
Sample: Nearly 500,000 people from the UK Biobank and 23andMe databases.
Method: Genome-wide association study (GWAS) — scanning the DNA of large groups to find genetic variants that are more common among people who report same-sex sexual behavior.
Findings:
No single “gay gene” — instead, they found five genetic markers with statistically significant links to same-sex behavior.
Each marker had a tiny effect size — they can’t predict orientation individually.
The combined genetic influence explained 8–25% of the variation in same-sex sexual behavior (estimates vary depending on the model).
Genes linked to sexual behavior overlapped with those influencing traits like risk-taking, openness to experience, and certain smell preferences — suggesting biological complexity.
Conclusion: Sexual orientation is polygenic (many genes involved) and interacts with non-genetic factors.
Earlier research:
Twin studies
Method: Comparing identical twins (share 100% of genes) vs. fraternal twins (share ~50%).
Findings: Identical twins are more likely to share the same sexual orientation than fraternal twins — but not always.
Example: If one identical twin is gay, the other has about a 20–40% chance of also being gay (much higher than the general population, but not 100%).
Conclusion: Genetics matter, but they’re not the whole story.
Biological & prenatal studies
Prenatal hormones: Exposure to different levels of testosterone or estrogen during fetal development can influence brain structures linked to sexual attraction.
Fraternal birth order effect: Men with more older brothers are statistically more likely to be gay — possibly due to immune responses in the mother during pregnancy.
2. Nature vs. Nurture in this context
Nature = factors you’re born with:
Your genes
Prenatal hormone environment
Possible early brain development patterns
Nurture = external/environmental influences:
Social upbringing and culture
Life experiences
Environmental conditions after birth
In sexual orientation research:
Evidence shows nature plays a significant role (genetic variants + biology before birth).
Nurture also plays a role — but not in the simplistic “someone is raised to be gay” sense. Instead, environmental influences may shape how genetic predispositions are expressed or how identity is formed over time.
Key takeaway
The consensus among scientists today:
Sexual orientation is not a choice.
It’s shaped by a complex interplay of genes, prenatal biology, and environmental factors.
No single “switch” determines orientation — it’s more like a web of small influences that together guide sexual preferences.
Meanwhile, here are some photos ( Photo Credit- J Shively) during One of the Many Enjoyable THD Activities- Painting Bird Houses for Our Patios.
2 comments:
David - I really like your reference to the twin studies which may be the best marker of genetic import with sexual orientation. Phil
Dear David,
I am a Personality Psychologist and in my earlier life I used to write about genetic and environmental influences on Personality and Intelligence. Your summary of the research findings relating to same-sex preference is quite accurate. Let me suggest one additional finding. Behavior Genetic models consider two different environmental influences - those shared by common family influences and environmental influences that are not shared by individuals reared in the same family. Personality (and homosexuality) exhibit near zero shared environmental influences. the environmental influences are largely those that are independent of shared family rearing. There is also some evidence for geneticXEnvironmental influences that leads to lower resemblance of siblings reared together. Nathan Brody
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